When a missing young woman, Christina, suddenly reappears in the Mexican desert, her peculiar death threatens to unearth a horrific secret. A US Border Agent narrowly escapes being murdered by two mysterious men, Sideburns and Mustache, who have been feverishly hunting an elusive quarry - James, an escaped hostage. Turner, a deep-cover spy, reaches out to his superior, the machiavellian General, to warn him of a potential breach in one of their clandestine labs - an abandoned factory now home to heinous human experimentation. And a routine traffic stop turns deadly, forever changing the life of a young lawman, Cotton.